Tranexamic Acid

Tranexamic Acid

China H&Z® Tranexamic Acid is a white powder that is an effective skin lightener when used in cosmetic formulations. The lightening effects of tranexamic acid were discovered accidentally during a medical procedure.
Tranexamic acid works by stopping tyrosinase activity, which reduces the formation of melanin. It is soluble in water and glacial acetic acid (anhydrous). Our tranexamic acid has been assayed at 99+% pure.
Please note that this is for COSMETIC USE ONLY, not to be consumed, injected, or used in any way other than as a topical cosmetic ingredient. Tranexamic acid must be formulated into a cosmetic cream, lotion, or serum, it cannot be applied directly to skin in its powdered form.

Product Detail

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China Tranexamic Acid Factory


Tranexamic acid CAS:1197-18-8

Tranexamic acid Chemical Properties
MF:C8H15NO2
MW:157.21
EINECS:214-818-2
Melting point:>300 °C(lit.)
Boiling point:281.88°c (rough estimate)
Density:1.0806 (rough estimate)
Refractive index:1.4186 (estimate)
Solubility:Freely soluble in water and in glacial acetic acid, practically insoluble in acetone and in ethanol (96 per cent).
Pka:Pka 4.3 (uncertain);10.6 (uncertain)
Water Solubility:1g/6ml
Merck:14,9569
BRN:2207452

Tranexamic acid CAS:1197-18-8 Introduction:
H&Z® Tranexamic acid is a synthetic derivative of the amino acid lysine. It is used to treat or prevent excessive blood loss during surgery and in various other medical conditions. It is anantifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, by binding to specific sites of both plasminogen and plasmin, a molecule responsible for the degradation of fibrin, a protein that forms the framework of blood clots. Tranexamic acid has roughly eight times theantifibrinolytic activity of an older analogue, ε-aminocaproic acid. 
Tranexamic acid has been found to decrease the risk of death in people who have significant bleeding due to trauma. However, it may actually increase the risk of death due to bleeding if administered more than 3 hours after the injury

Tranexamic acid CAS:1197-18-8 Specification:

Items

Standards

Results

Physical Analysis

 

 

Description

White Crystalline Powder

Complies

Assay

98%

98.62%

Mesh Size

100 % pass 80 mesh

Complies

Ash

≤5.0%

2.85%

Loss on Drying

≤5.0%

2.65%

Chemical Analysis

 

 

Heavy Metal

≤10.0 mg/kg

Complies

Pb

≤2.0 mg/kg

Complies

As

≤1.0 mg/kg

Complies

Hg

≤0.1mg/kg

Complies

Microbiological Analysis

 

 

Residue of Pesticide

Negative

Negative

Total Plate Count

≤1000cfu/g

Complies

Yeast&Mold

≤100cfu/g

Complies

E.coil

Negative

Negative

Salmonella

Negative

Negative


Tranexamic acid CAS:1197-18-8 Function:
1Post-partum bleeding
A large, international study was conducted on the use of tranexamic acid after childbirth to prevent hemorrhaging. The trial found that tranexamic acid significantly reduced the risk of death from hemorrhaging after childbirth.
2.Mouthwash for oral procedures
An antifibrinolytic mouthwash can be used for controlling bleeding after an oral procedure such as a tooth extraction. The tranexamic acid mouthwash is used prior to the procedure and immediately afterwards to prevent and reduce bleeding.
3.Melasma
Topically applied tranexamic acid has been shown to significantly improve the appearance of melasma.

Tranexamic acid CAS:1197-18-8 Application:
1. Trauma: Tranexamic Acid Powder has been found to decrease the risk of death in people who have significant bleeding due to trauma. 
2. Heart surgery: Tranexamic Acid is commonly used in cardiac surgery, both with and without cardiopulmonary bypass. 
3. Orthopedic surgery: Tranexamic Acid Powder is used in orthopedic surgery to reduce bloodloss. 
4. Menstrual bleeding:Used as firstline nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids. 
5. Dentistry: Tranexamic Acid Powder is used in dentistry in the form of a 5% mouth rinse after extractions or surgery in patients with prolonged bleeding time, e.g. from acquired or inherited disorders.
6.In hemophilia: Tranexamic Acid Powder is also useful in the treatment of bleeding as a second line treatment after factor VIII in patients (e.g. tooth extraction).
7.Whitening effect: Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%.    
8.H&Z® Tranexamic Acid Powder is used for Comestics,freckle whitening an so on. 



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