China H&Z® Oleanic Acid Factory
Oleanolic Acid CAS:508-02-1
Oleanolic Acid Source: Olive Leaf Extract ,Ligustrum lucidum extract
Oleanolic Acid Introduction:
Oleanolic acid is a pentacyclic triterpenoid derived from the fruit of the genus Asteraceae, Syzygium sylvestris, or Ligustrum lucidum, which is present in the free body and glycoside.
Plants have become clinically used hepatoprotective drugs, which have obvious protective effects on acute and chronic liver damage caused by carbon tetrachloride, which can increase elevated ALT and AST, inflammation, necrosis and interstitial inflammation.
The reaction is relieved, the formation of fibrosis is prevented, the regeneration of hepatocytes is promoted, and the recovery of necrotic tissue is accelerated.
Oleanolic Acid Specification:
|
Items |
Standard (NF11) |
|
Appearance |
Off-white to white powder |
|
Odor |
Characteristic |
|
Identification |
TLC: Positive |
|
Taste |
Characteristic |
|
Particle Size |
NLT 95% pass 80 mesh |
|
Loss on Drying |
≤5.0% |
|
Residue on Ignition |
≤1.0% |
|
Heavy Metals |
≤10ppm |
|
Assay(HPLC) |
≥98% |
|
Total Plate Count |
≤1000cfu/g |
|
-Yeast & Mold |
≤100cfu/g |
|
-E.Coli |
Negative |
|
-Salmonella |
Negative |
Oleanolic Acid Functions:
1. H&Z® Oleanolic acid has anti-inflammatory, sedative, cardiotonic, diuretic, hypolipidemic, hypoglycemic and liver-lowering enzymes, enhances immunity and inhibits the growth of S180 tumor cells. It is an effective ingredient for the development of drugs for the treatment of liver diseases and blood sugar lowering.
2. Oleanolic acid has a protective effect on chromosomal damage and has a preventive effect on experimental atherosclerosis.
3. Oleanolic acid has the effect of inhibiting hepatic fibrosis. In rats with liver fibrosis treated with oleanolic acid, hepatic fibrosis is severely and significantly reduced, and the content of hepatic collagen is reduced, suggesting that it has the effect of preventing and treating liver cirrhosis.
4. Reducing the level of tyrosine in brain homogenate of rats with cirrhosis.
Oleanolic Acid Application
1. Applied in food field, it can acts as raw materials of tea to reduce phlegm;
2. Applied in pharmaceutical field, it becomes a new anti-cancer drug with low toxic;
Clinically, it is mainly used for the treatment of acute icteric hepatitis, with significant curative effect and good effect on chronic hepatitis.
The symptoms, signs and liver function have been significantly improved. In addition, it also corrects protein metabolism disorders.
3. Applied in cosmetic field, it can invigorate blood circulation and remove beverage.
