D-Glucurone

D-Glucurone

D-Glucurone of H&Z® factory is a naturally occurring substance that is an important structural component of nearly all connective tissues.Glucuronolactone is also found in many plant gums.
Glucuronolactone is hydrolyzed in the body to glucuronic acid, which may be oxidized to glucaric acid, or isomerized to another hexuronic acid, so there is no reasonable toxicity mechanism.

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D-Glucurone/Glucuronolactone CAS:32449-92-6

D-Glucurone Chemical Properties
MF:C6H8O6
MW:176.12
EINECS:251-053-3
Melting point:172-175 °c(lit.)
Alpha:19 º (c=10, h2o)
Boiling point:227.71°c (rough estimate)
Density:1,76 g/cm3
Refractive index:18.5 ° (c=5, h2o)
Solubilitywater: Soluble25mg/ml, clear, colorless
Pka:11.96±0.60(predicted)
Optical activity:[α]24/D +18.8°, c = 8 in H2O
Water Solubility:SOLUBLE

D-Glucurone/Glucuronolactone CAS:32449-92-6 Specification:

Item

Specifications

Results

Appearance

White crystalline or white crytstalline powder

Complies

Identification

Positive

Positive

Melting point

170~176℃

174.2℃

Specific rotation

+18.0~20.0

+19.2°

Appearance of solution

Clarity& colorless

Conforms

Loss on drying

≤0.5%

0.05%

Residue on ignition

≤0.1%

0.06%

Sulphate(SO4)

≤1ppm

<1ppm

Ammonium salts(NH4)

≤200ppm

<200ppm

Heavy metals

≤10ppm

<10ppm

Assay

98.5~102.0%

100.3%

Total plate count

≤1000cfu/g

<1000 cfu/g

Yeast&Mold

≤100cfu/g

<100cfu/g

E-Coli

Negative/25g

Negative

Salmonelle

Negative/375g

Negative

Staphylococcus aureus

Negative/25g

Negative

Coliforms

Negative/25g

Negative

Conclusion

The results conforms with CP2015 standards


D-Glucurone/Glucuronolactone CAS:32449-92-6 Function:
1.Glucuronolactone is metabolized to glucaric acid, xylitol, and L-xylulose, and humans may also be able to use glucuronolactone as a precursor for ascorbic acid synthesis
2.Glucuronolactone is also used as a detoxicant The liver uses glucose to create glucuronolactone, which inhibits the enzyme B-glucuronidase (metabolizes glucuronides), which should cause blood-glucuronide levels to rise. 
3.Glucuronolactone is a popular ingredient in energy drinks with claims that it detoxifies the body. 
4.Glucuronolactone can be combined with the liver and intestinal toxicants to form a non-toxic glucuronic acid conjugate, so it has liver and detoxification effects. 
5.Glucuronolactone is clinically used for the treatment of hepatitis, cirrhosis, jaundice, rheumatism, etc. It is also used as an antidote to food and drug poisoning.

D-Glucurone/Glucuronolactone CAS:32449-92-6 Application:
1.H&Z® D-Glucurone/Glucuronolactone can be applied for Nutritional supplement;
2.D-Glucurone/Glucuronolactone can be applied for Nutrition enhancer;
3.D-Glucurone/Glucuronolactone can be applied for Dietary supplements;
4.D-Glucurone/Glucuronolactone can be applied for Heatlh food additives;
5.D-Glucurone/Glucuronolactone can be applied for Pharmaceutical raw material;sport supplements;
6.D-Glucurone/Glucuronolactone can be applied for Sport nutrtional supplements;
7.D-Glucurone/Glucuronolactone can be applied for Bodybuilding supplement.



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