China Albendazole Factory
Albendazole CAS:54965-21-8
Albendazole Chemical Properties
MF:C12H15N3O2S
MW:265.33
EINECS:259-414-7
Melting point:208-210°c
Density:1.2561 (rough estimate)
Refractive index:1.6740 (estimate)
Solubilitypractically insoluble in water, freely soluble in anhydrous formic acid, very slightly soluble in methylene chloride, practically insoluble in ethanol (96 per cent).
Pka:10.72±0.10(predicted)
Water Solubility:0.75mg/L(209ºC)
Albendazole CAS:54965-21-8 Specification:
|
Items |
Specification |
|
Appearance |
White or almost white powder |
|
Identification |
Positive |
|
Loss on Drying |
≤0.5% |
|
Residue on Ignition |
≤0.2% |
|
Related Compounds |
≤1.5% |
|
Melting Point |
206.0-212.0°C |
|
Particle Size |
≤20 Microns |
|
Assay(on dried basis) |
≥98.5% |
|
Standard |
CP2010 |
|
Items |
Specification |
|
Appearance |
White or almost white powder |
|
Identification |
Positive |
|
Loss on Drying |
≤0.5% |
|
Residue on Ignition |
≤0.2% |
|
Related Compounds |
≤0.5% |
|
Particle Size |
≤20 Microns |
|
Assay(on dried basis) |
98.0~102.0% |
|
Standard |
USP37 |
Albendazole CAS:54965-21-8 Introduction:
1. H&Z® Albendazole is a kind of broad spectrum thiabendazole class anthelmintics which can be applied by both human and animal.
2. Albendazole can inhibit the parasite growth and reproduction by inhibiting the intestinal and absorbing the intracellular protein, resulting in the failure of parasite in sugar uptake which is indispensable for their survival, thus causing the endogenous glycogen depletion of insects and further inhibiting fumarate reductase system, preventing the generation of adenosine triphosphate, causing that the parasites are not be able to further survive and reproduce, and ultimately die due to energy depletion.
Albendazole CAS:54965-21-8 Functions
H&Z® Albendazole is an anthelmintic or anti- worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.
Albendazole is used to treat certain infections caused by worms such as pork tapeworm and dog tapeworm.
1. Albendazole is highly effective broad spectrum anthelmintic drugs, is benzimidazole deworming drugs in the broader spectrum.
2. Albendazole is highly active against nematodes, schistosomes, tapeworms, but also significantly inhibited the development of eggs.
3. Albendazole on parasitic nematodes in a variety of animals, schistosomes, tapeworms and cysticerci also has a significant role in repelling.
4. Albendazole is applied to get rid of roundworm, pinworm, hookworm, whipworm, can also be used for deworming livestock.
Albendazole CAS:54965-21-8 Application:
1. Broad spectrum antiparasitic; Used to expel nematode, tapeworms, trematode worms and ectoparasites in livestock.
2. Albendazole has a broad spectrum of insect repellents, and has a strong effect on nematode, tapeworm and trematode; Its mechanism of action is to bind to microtubulin in the worm and prevent it polymerize withα-tubulin to form microtubules, thus affecting cell reproduction processes such as mitosis, protein assembly and energy metabolism.
3. Ivermectin has a good effect on the internal and external parasites, especially arthropod insects and internal nematode worms; It is mainly used to expel the gastrointestinal nematodiasis, lungworm and ectoparasites; The mechanism of deworming is to promote the release of GABA by presynaptic neurons, thus opening GABA-mediated chloride ion channels; Chlorine ion flow can reduce the resistance of cell membrane, cause the slight depolarization of the postsynaptic membrane static potential, interfere with the signal transmission between the nerve muscles, and also cause the insect body to relax and paralyze, resulting in the death or expulsion of the insect body.
